There are early evidences of Giotto's panel painting. These panels were executed around 1300 and they betray signs of his having studied contemporary Florentine sculpture. In comparison with his earlier works, the better development of space and more logical use of consistent perspective are new to all later panels. He received numerous commissions for altarpieces that he executed with his workshop. Both works by his atelier and by pupils, and those executed by his own hand, testify to its activities. However, the majority of panel paintings can no longer be seen in their original context. They were for the most part taken to pieces, and the few individual pieces that remain are scattered around the museums of the world.
| Summary of paintings by Giotto |
| Frescoes in the San Francesco, Assisi |
| Legend of St. Francis | New Testament scenes | Lower Church |
| Frescoes in the Arena Chapel, Padua |
| Life of Joachim | Life of Virgin | Life of Christ | Last Judgment | Angels | Decoration |
| Frescoes in the S. Croce, Florence |
| Frescoes in the Peruzzi Chapel | Frescoes in the Bardi Chapel |
| Panel paintings |
| Crucifix | Maestŕ and others | Polyptych panels | Srefaneschi Altarpiece | Baroncelli Polyptych |
| Miscellaneous works |
| The Navicella mosaic | The Campanile of the Florence Cathedral |