This lyrical picture - located in the south arm of the western transept below the great Crucifixion scene - is one the earliest example of the Santa Conversazione. The visionary half-length apparitions rise up from behind a stone ledge, set against the infinite gold beyond.
Below, on the narrow predella the Crucifix in golden background can be seen between the coat-of-arms of the Orsini Family. On the right is the profile portrait of the donor. On the left probably a woman portrait has been lost.
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