The Santa Trinita (Holy Trinity) church was erected in the 13th century. It was rebuilt several times and the present Baroque fašade was made only at the end of the 16th century by Bernardo Buontalenti. The interior was restored in Gothic style at the end of the 19th century. The church is famous for the Sassetti Chapel decorated in 1486 by Domenico Ghirlandaio with frescoes of the life of St Francis.
You can find more information on the Santa Trinita in the Wikipedia.
Recommended viewing from the collection:
The Web Gallery of Art contains 43 images of artworks from the Santa Trinita.