Ignazio Secondo Collino and his brother Filippo Collino worked together on many occasions, so that most of their output cannot be definitely attributed to one or the other. Ignazio was first taught drawing by Claudio Francesco Beaumont and sculpture by François Ladatte. In 1748 he went to study sculpture under Giovanni Battista Maini in Rome, where Filippo joined him in 1754. The brothers' earliest works are copies from the Antique. Two marble profile portraits in low relief of Alexander the Great and Alexander's mother Olympia (both 1754; Turin, Palazzo Reale), which presage the Neo-classical style, are known to be by Filippo.