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The painting depicts a landscape with Latona and her children and the Lycian peasants being turned into frogs.
The legend of Latona is the following. Latona, mother of Apollo and Diana and mistress of Jupiter, was forced to flee owing to the jealousy of her rival Juno. One day, after arriving in present-day Turkey, she approached a pool in a marsh to drink the water. Local peasants prevented her and in her fury she laid a curse on them which changed them into frogs. This episode is recounted by Ovid in the Book VI of his Metamorphoses.
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