In 1442, with Medici support, Pope Eugenius IV awarded Lippi an important benefice. A large payment was made in 1447 for St Bernard's Vision of the Virgin (National Gallery, London), produced for the Palazzo della Signoria, as well as final payments for the Coronation of the Virgin, made for Sant'Ambrogio, which was commissioned in 1441.

The Annunciation in the Church of San Lorenzo is among the most successful paintings of Lippi's middle period, with a daring balance of figures, architecture, and landscape. The Annunciation appears to utilize the natural sources within the church itself, which was designed by Filippo Brunelleschi.

Many critics have presumed an interlude during the late 1440s when Fra Filippo was strongly attracted to the painting of Fra Angelico to such a point that a direct collaboration between the two masters has been postulated for the Adoration of the Magi, a tondo rich in detail and incidentals.

Preview	Picture Data	Info
	Madonna and Child c. 1440 Tempera on panel, 79 x 52 cm National Gallery of Art, Washington
	Madonna and Child (detail) c. 1440 Tempera on panel National Gallery of Art, Washington
	Portrait of a Man and a Woman c. 1440 Tempera on wood, 64 x 42 cm Metropolitan Museum of Art, New York
	Portrait of a Man and a Woman (detail) c. 1440 Tempera on wood Metropolitan Museum of Art, New York
	Portrait of a Woman 1440-42 Tempera on wood, 50 x 33 cm Staatliche Museen, Berlin
	Annunciation with two Kneeling Donors c. 1440 Oil on panel, 155 x 144 cm Galleria Nazionale d'Arte Antica, Rome
	Annunciation with two Kneeling Donors (detail) c. 1440 Oil on panel Galleria Nazionale d'Arte Antica, Rome
	Annunciation with two Kneeling Donors (detail) c. 1440 Oil on panel Galleria Nazionale d'Arte Antica, Rome
	Annunciation with two Kneeling Donors (detail) c. 1440 Oil on panel Galleria Nazionale d'Arte Antica, Rome
	Annunciation c. 1443 Wood, 203 x 186 cm Alte Pinakothek, Munich
	Annunciation (detail) c. 1443 Wood Alte Pinakothek, Munich
	Annunciation (detail) c. 1443 Wood Alte Pinakothek, Munich
	Annunciation (detail) c. 1443 Wood Alte Pinakothek, Munich
	Annunciation (detail) c. 1443 Wood Alte Pinakothek, Munich
	Coronation of the Virgin 1441-47 Tempera on wood, 200 x 287 cm Galleria degli Uffizi, Florence
	Coronation of the Virgin (detail) 1441-47 Tempera on wood Galleria degli Uffizi, Florence
	Coronation of the Virgin (detail) 1441-47 Tempera on wood Galleria degli Uffizi, Florence
	Coronation of the Virgin (detail) 1441-47 Tempera on wood Galleria degli Uffizi, Florence
	Coronation of the Virgin (detail) 1441-47 Tempera on wood Galleria degli Uffizi, Florence
	Coronation of the Virgin (detail) 1441-47 Tempera on wood Galleria degli Uffizi, Florence
	Coronation of the Virgin (detail) 1441-47 Tempera on wood Galleria degli Uffizi, Florence
	Coronation of the Virgin (detail) 1441-47 Tempera on wood Galleria degli Uffizi, Florence
	Coronation of the Virgin 1441-45 Wood, 167 x 69, 172 x 93, 167 x 82 cm Pinacoteca, Vatican
	Adoration of the Magi c. 1445 Tempera on wood, diameter 137 cm National Gallery of Art, Washington
	Adoration of the Magi (detail) c. 1445 Wood National Gallery of Art, Washington
	Adoration of the Magi (detail) c. 1445 Wood National Gallery of Art, Washington
	Annunciation c. 1445 Wood, 175 x 183 cm San Lorenzo, Florence
	Annunciation c. 1445 Wood, 175 x 183 cm San Lorenzo, Florence
	Annunciation (detail) c. 1445 Wood San Lorenzo, Florence
	Annunciation (detail) c. 1445 Wood San Lorenzo, Florence
	Annunciation (detail) c. 1445 Wood San Lorenzo, Florence
	Madonna Enthroned with Saints c. 1445 Tempera on wood, 196 x 196 cm Galleria degli Uffizi, Florence
	Madonna Enthroned with Saints (detail) c. 1445 Tempera on wood Galleria degli Uffizi, Florence
	Madonna Enthroned with Saints (detail) c. 1445 Tempera on wood Galleria degli Uffizi, Florence
	Madonna Enthroned with Saints (detail) c. 1445 Tempera on wood Galleria degli Uffizi, Florence
	Meeting of Joachim and Anne at the Golden Gate c. 1445 Tempera on wood, 21 x 48 cm Ashmolean Museum, Oxford
	The Virgin Appears to St Bernard 1447 Wood, 69 x 105 cm National Gallery, London
	Annunciation 1445-50 Tempera on panel, 117 x 173 cm Galleria Doria Pamphilj, Rome
	Annunciation 1448-50 Egg tempera on wood, 68 x 152 cm National Gallery, London
	Annunciation (detail) 1448-50 Egg tempera on wood National Gallery, London
	Annunciation (detail) 1448-50 Egg tempera on wood National Gallery, London
	Seven Saints 1448-50 Egg tempera on wood, 68 x 151 cm National Gallery, London