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The altarpiece was commissioned for the small chapel, adjacent to the castle of Burg Weiler, one of the seats of the Freiherren von und zu Weiler.
The central panel of the three-part altarpiece shows the Virgin and Child standing on a crescent moon, flanked by saints, Apollonia and Barbara to the left and Catherine of Alexandria and Lawrence to the right. On the left interior wing are two local saints, Jodokus and Wendelin, on the right interior wing Sebastian and Maurice. The saints prominently display their identifying attributes, and their halos are plain disks tooled in the gold ground.
Formerly the altarpiece was considered to be a work by a Middle-Rheinish painter in the circle of the Master of the Housebook. Now it is attributed to master working in the northern reaches of Swabia, perhaps in Heilbronn.
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