There is early evidence of Giotto's panel paintings. These panels were executed around 1300, and they betray signs of his having studied contemporary Florentine sculpture. In comparison with his earlier works, the better development of space and more logical use of consistent perspective is new to all later panels. He received numerous commissions for altarpieces that he executed with his workshop. Both works by his atelier and pupils, and those executed by his own hand, testify to its activities. However, most of his panel paintings can no longer be seen in their original context. They were mostly taken to pieces, and the few individual pieces that remain are scattered around the museums of the world.
The mosaic of Navicella in the atrium of the Old St. Peter's in Rome, now almost totally lost, is attributed to Giotto. The giant mosaic has originally occupied the whole of the wall above the entrance arcade facing the courtyard. Unfortunately, this extraordinary work has been destroyed in the course of its history.
On 14 April 1334, the city of Florence appointed Giotto Master of Municipal Construction Works and the Cathedral Masons' Guild (capomaestro). In July 1334, the foundation stone of the bell tower (campanile) of the cathedral was laid - we can assume that the newly appointed capomaestro would have been given overall control of the building work. However, only the lower story of the bell tower was realized from this design.