The panel of the Lamentation in its original arrangement, mounted in an antique frame with pillars in which were represented seven saints, once enriched the scenography of the high altar of the ancient church of St Margaret in Cortona. This was surely admired by Pope Leo X when, during a stop on his way to Bologna to meet Francis I of France, he visited the church in 1515. In the second half of the 1700s the painting was moved, deprived of its frame, and finally placed in the choir of the cathedral of its origin.

The Lamentation, a work done entirely the artist alone, reveals all the poetry of the painter even in the context of an unrefined style which may seem declamatory, scenic and rhetorical. In the predella that Signorelli probably painted with the help of his assistant, Gerolamo Genga, four scenes from the Passion of Christ are represented: The Prayer in the Garden; The Last Supper; The Capture; The Flagellation.

Preview	Picture Data	Info
	Lamentation over the Dead Christ 1502 Wood, 270 x 240 cm Museo Diocesano, Cortona
	Lamentation over the Dead Christ (with predella) 1502 Wood, 270 x 240 cm Museo Diocesano, Cortona
	Lamentation over the Dead Christ (detail) 1502 Wood Museo Diocesano, Cortona
	Lamentation over the Dead Christ (detail) 1502 Wood Museo Diocesano, Cortona
	Lamentation over the Dead Christ (detail) 1502 Wood Museo Diocesano, Cortona
	The Prayer in the Garden. 1502 Wood Museo Diocesano, Cortona
	The Last Supper 1502 Wood Museo Diocesano, Cortona
	The Capture of Christ 1502 Wood Museo Diocesano, Cortona
	The Flagellation 1502 Wood Museo Diocesano, Cortona