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The painting of the Virgin and Child with St Anne, which the Nuremberg patrician Leonardo Tucher commissioned from Dürer as a devotional picture, was preceded by several preliminary studies. The picture became very famous and in later centuries was copied a total of seven times. The monumental main figure of St Anne is a portrait of Agnes Dürer. Together with Mary - wearing the costume of a Nuremberg citizen - and the sleeping Christ Child, she forms an acute-angled triangle. St Anne's pensive gaze and the figure of the sleeping boy refer to the Passion of Christ.
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