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The narrow north wall of the library contains two scenes, the fifth and the sixth of the cycle. The sixth scene shows Pope Calixtus III Borgia anointing Enea Silvio a cardinal on December 17, 1456. In that same ceremony the pope's nephew, Rodrigo Borgia - the later Pope Alexander VI - was elevated to the same dignity. The focus of the scene is the altar retable, a painting of the Madonna with Saints James and Andrew, the patron saints of the Piccolomini.
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