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The Breviary of Queen Isabella of Castile, the patroness of Christopher Columbus, was probably commissioned by Francisco de Rojas, a diplomat in her service, in about 1497. It was illuminated in Bruges and may have been intended for use in one of the royal chapels.
The miniature on folio 348r, shown here, illustrates the office of St Thomas Aquinas and shows the saint in church with the crucifix which miraculously spoke to him.
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