Italian architect. He was probably born in Venice into a family from Bergamo.
In 1652 he was commissioned to restore the façade of the church of San Clemente on the Isola di San Clemente. In 1653-54 he worked on an altar in the church of the new Venetian convent of the Carmelites of St. Theresa. The church and convent of St. Theresa were built by Cominelli for the Sisters of Saint Theresa and consecrated in 1688. He was credited with the design of the Palazzo Labia in Venice.