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This panel was part of a large altar-piece, probably made for a church in Cremona in the early 1520s, of which the centre panel with The Virgin and Child and the predella with scenes from the life of St Helena are known.
Altobello Melone, although Cremonese, looks forward in his enhanced naturalism to the School of Bologna in his Tobias and the Angel. A dishevelled, sleepy-eyed angel leads diminutive Tobias, with his small fish, by the hand.
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