The Catacombs of San Callisto, located along the Via Appia Antica, were built after AD 150, with some private Christian hypogea and a funeral area directly dependent on the Catholic Church. It takes its name from the deacon Saint Callixtus, proposed by Pope Zephyrinus on his accession as pope. The Pope enlarged the complex, that soon became the official one for the Roman Church. The arcades, where more than fifty martyrs and sixteen pontiffs were buried, form part of a complex graveyard that occupies fifteen hectares and is almost 20 km long.
The catacombs are most notable for containing the Crypt of the Popes (Italian: Cappella dei Papi), which once contained the tombs of several popes from the 2nd to 4th centuries.
| Catacomb paintings |
| Domitilla | Marcellinus and Peter | Priscilla |
| Callixtus | Via Latina | Others in Rome |